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When you get injured or your immune system detects a potentially dangerous foreign substance, certain white blood cells and tissue cells release histamines that seek out and attach to other cells that have a histamine receptor.
Here, the histamines induce an inflammatory response — they dilate the blood vessels, increasing blood flow to the site of injury or invasion.
Non-drowsy antihistamines are generally the best option, as they're less likely to make you feel sleepy.
This page covers: Types of antihistamines How to take them Side effects Taking them with other medicines, food or alcohol Who can take them – including pregnancy advice How they work There are many types of antihistamine.
Topical antihistamine creams, present in many forms of over-the-counter anti-itch creams, should not be used for the treatment of hives or other skin allergies.